The present invention is directed to a porcine xenoantigen that does not include an aGal epitope; also directing to agents which bind to the porcine xenoantigen. Organ transplantation has become the treatment of choice for various diseases associated with organ failure. However, the supply of organs from organ donors falls far short of meeting the rapidly increasing demand. One attractive approach to overcoming this shortage is to use animals as a source of organs for transplantation (a process known as xenotransplantation). In recent years, a consensus has emerged that the domestic pig may represent a good alternative to nonhuman primates as a donor of organs for transplantation.
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